Maternal hemoglobin level and fetal outcome at low and high altitudes

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Maternal hemoglobin level and fetal outcome at low and high altitudes.

Both, low (<7 g/dl) and high (>14.5 g/dl), maternal hemoglobin (Hb) levels have been related to poor fetal outcome. Most studies have been done at low altitude (LA). Here, we have sought to determine whether this relationship exists at both high and low altitude, and also whether there is an adverse effect of high altitude (HA) on fetal outcome independent of level of maternal hemoglobin. The s...

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Eaton et al. (1) stated that "increased, rather than decreased, oxygen affinity is an effective mode of short-term adaptation to markedly reduced environmental oxygen pressures" and pointed out the need to reevaluate the idea that "decreased hemoglobin-oxygen affinity is of adaptive value to humans at high altitudes." We fully agree with these authors and wish to call attention to the fact that...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

سال: 2009

ISSN: 0363-6119,1522-1490

DOI: 10.1152/ajpregu.00275.2009